My wife loves her PPK and has no problems with it cutting her hand. I can shoot it without cutting my hand but I have to double check the placement of the gun in my hand before I shoot just to make sure. My dad has been shooting a PPK for about 15 years and has permanent marks on his hand from the numerous cuts he has accumulated. It really depends on hand size.
Weight: the PPK/S weighs 51 g (1.8 oz) more than the PPK
The PPK/S magazine holds one additional round, in both calibers.
The version currently manufactured by Smith & Wesson has been modified by incorporating a longer grip tang, better protecting the shooter from slide bite, i.e. the rearward-traveling slide's pinching the web between the index finger and thumb of the firing hand, which was a problem with the original PPK design.