For 9 MM I generally shoot Hydra-Shocks. In .45 ACP Critical Defense is good. Sometimes I'll change off if Cabela's has a sale going on some of the other brand name stuff. I live just 2 miles away, so I generally wind up there at least once a week or so.
Through several training classes, and many LE stories, I've learned and respected the "no magic bullet" theory. And what little I've seen and heard, it seems (IMO) the heavier the slug, the better. The FBI ballistics tests that I've seen seem to weigh (no pun intended) in favor of a heavier, slow(er) moving slug as opposed to a light one going much faster.
Depending on your school of thought, or which ever way you tend to lean, it all boils down to this- Shot placement is king.
Dosent matter if you're slingin' a 235g chunk-o-lead or a 115g hollowpoint, if that slug hits em' in the electrical box, you're gonna shut em' down...and fast.