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Here is a cool chart showing the penetration and cavity using different calibers . I suppose you guessed 45 was the most destructive . 9mm faired petty well IMO

 

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This thing is old. I'm not sure how old, exactly, but it's been floating around for years. It's a nice graphic, but most people look at it and really have no idea what they're looking at.

The big part on the left side of the chart is, in flesh, the temporary cavity and has been proven to be meaningless when it comes to having any impact on a shooting, unless it's in the head. The tissue in the body rebounds from the temporary cavity with almost no permanent damage. The smaller lines after the end of the temporary cavity is the permanent cavity and is the damage the bullet actually does. A realistic look would be to cut all of the temporary cavity out of the picture.

Here's some good reading on the subject:

http://ammo.ar15.com/project/Self_Defense_Ammo_FAQ/index.htm
http://www.m4carbine.net/showthread.php?t=22323
http://www.firearmstactical.com/pdf/fbi-hwfe.pdf (This might just be about the same age as this image, but the info is still fairly valid)
http://www.greent.com/40Page/ammo/
 
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