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Glockn Rollin
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I was part of a conversation yesterday with a group of LEO's concerning the best self defense ammo. The conversation ranged from 380, S&W 40 cal, 357, and 45 cal. I hear the term "knock down power" or "stopping power." Knock down power is not really a correct term as the energy needed to knock someone down (as seen in the movies with flying body's after being shot) would also be transferred to the shooter. I spoke about the fact of the matter remains, the larger area that the bullet can damage, the better chances you have to stop or terminate the aggressors abilty to continue the attack. Of couse bullet placement has the most effect on the out come also, so marksmanship skills to count.
Yep this pretty much sums it up. There are so many variables that you honestly can't say one bullet or caliber is better than the other in handguns (unless you're talking .44 mag or .500 S&W). With the less-powerful calibers (9mm, .40 S&W, .45ACP) calibers, it really does depend on where you shoot them, and then how much area is damaged and how much force is transmitted into the target's body. If it has 10,000 lbs of force but the bullet sails right through them without displacing much energy, it does no good.

Unless you are talking central nervous system of a heart shot, the larger diameter (larger area damaged) of the bullet, and how much force it TRANSFERS not how much it says it has on the box, and the amount of blood loss that wound causes are the determining factors.
 
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